Concepedia

B7+CTLA4+ T cells engage in T–T cell interactions that mediate apoptosis: a model for lentivirus-induced T cell depletion

Thomas W. Vahlenkamp, Marta E. Bull, Janet L. Dow, Ellen W. Collisson, Barbara J. Winslow, Anagha P. Phadke, W. A. F. Tompkins, Mary B. Tompkins

Veterinary Immunology and Immunopathology · 2004 · 19 citations · 43 references

DOI

Concepts

References

43

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

, , +14

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

Lawrence Boise, Andy J. Minn, Patricia J. Noel et al. · Immunity · 1995 · 1.2K citations · Full text

, , +13

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

P S Linsley, William Brady, Laura S. Grosmaire et al. · The Journal of Experimental Medicine · 1991 · 1.1K citations · Full text

, , +17

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

P S Linsley, JoAnne L. Greene, William Brady et al. · Immunity · 1994 · 972 citations

, , +15

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

Terri H. Finkel, Gareth Tudor‐Williams, Nirmal K. Banda et al. · Nature Medicine · 1995 · 948 citations

, , +15