Publication | Open Access

Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: A novel, potent and orally active direct inhibitor of factor Xa

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignMechanism Of ActionPharmacological AgentFactor XaPharmacotherapyDrug DevelopmentPharmacologyActive Direct InhibitorPharmaceutical ChemistryDrug Discovery