Concepedia

Mre11 Nuclease Activity Has Essential Roles in DNA Repair and Genomic Stability Distinct from ATM Activation

Jeffrey Buis, Yipin Wu, Yibin Deng, Jennifer L. Leddon, Gerwin Westfield, Mark Eckersdorff, JoAnn Sekiguchi, Sandy Chang, David O. Ferguson

Cell · 2008 · 338 citations · 42 references

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42

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

Andrew J. Pierce, Roger D. Johnson, L.H. Thompson et al. · Genes & Development · 1999 · 1.4K citations · Full text

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Human CtIP promotes DNA end resection

Alessandro A. Sartori, Claudia Lukas, Julia Coates et al. · Nature · 2007 · 1.3K citations · Full text

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The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

Grant S. Stewart, Richard S. Maser, Debra A. Bressan et al. · Cell · 1999 · 1.1K citations · Full text

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Requirement of the MRN complex for ATM activation by DNA damage

Tamar Uziel, Yaniv Lerenthal, Lilach Moyal et al. · The EMBO Journal · 2003 · 1.1K citations · Full text

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