Concepedia

Methylated DNA Causes a Physical Block to Replication Forks Independently of Damage Signalling, O6-Methylguanine or DNA Single-Strand Breaks and Results in DNA Damage

Petra Groth, Simon Ausländer, Muntasir Mamun Majumder, Niklas Schultz, Fredrik Johansson, Eva Petermann, Thomas Helleday

Journal of Molecular Biology · 2010 · 79 citations · 56 references

DOI

Concepts

References

56

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

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Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Lee Zou, Stephen J. Elledge · Science · 2003 · 2.7K citations

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

Sylvie Doublié, Stanley Tabor, Alexander Long et al. · Nature · 1998 · 1.2K citations

, , +14

MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

Manuel Stucki, Julie A. Clapperton, Duaa H. Mohammad et al. · Cell · 2005 · 1.1K citations · Full text

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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Jann N. Sarkaria, Ericka C. Busby, Randal S. Tibbetts et al. · PubMed · 1999 · 1K citations

, , +16