Jann N. Sarkaria

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.5K citations · Full text

Neuro-oncology, Oncology, Tumor Heterogeneity +13

A role for ATR in the DNA damage-induced phosphorylation of p53

Randal S. Tibbetts, Kathryn M. Brumbaugh, Jean Williams et al. · Genes & Development · 1999 · 1K citations · Full text

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Jann N. Sarkaria, Ericka C. Busby, Randal S. Tibbetts et al. · PubMed · 1999 · 1K citations

Protein Kinase Activities, Atr Kinase Activities, Radiation Biology +17

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

Kui Ming Chan, Fang Dong, Haiyun Gan et al. · Genes & Development · 2013 · 692 citations · Full text

Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells

Anand G. Patel, Jann N. Sarkaria, Scott H. Kaufmann · Proceedings of the National Academy of Sciences · 2011 · 534 citations

Homologous Recombination-deficient Cells, Genome Instability, Parp Inhibition +13