Concepedia

Replication Through Dna Damage

Replication Through DNA Damage is a molecular mechanism in DNA replication that enables the replication fork to bypass obstructive DNA lesions via specialized polymerases or recombination-mediated pathways, thereby maintaining genome integrity under genotoxic stress.

307

Publications

20.5K

Citations

1.3K

Authors

438

Institutions

Publications per year

2017–2026

57

Parents

Publications

307

Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ

John Nelson, Christopher W. Lawrence, David C. Hinkle · Science · 1996 · 653 citations

, , +14

The DNA Replication and Damage Checkpoint Pathways Induce Transcription by Inhibition of the Crt1 Repressor

Mingxia Huang, Zheng Zhou, Stephen J. Elledge · Cell · 1998 · 515 citations · Full text

, , +16

The Mutagenesis Protein UmuC Is a DNA Polymerase Activated by UmuD′, RecA, and SSB and Is Specialized for Translesion Replication

Nina Reuven, Gali Arad, Ayelet Maor-Shoshani et al. · Journal of Biological Chemistry · 1999 · 374 citations · Full text

, , +16

Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA

Viola Ellison, Bruce Stillman · PLoS Biology · 2003 · 364 citations · Full text

, , +17

Replication‐mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA‐dependent protein kinase and dissociates RPA:DNA‐PK complexes

Rhong-Guang Shao · The EMBO Journal · 1999 · 341 citations · Full text

, , +17

1–5 of 307

Authors

1.3K

  1. SP
    Satya Prakash

    The University of Texas Medical Branch at Galveston, United States

    10 publications · 1K citations

    10

    h-index

  2. LP
    Louise Prakash

    The University of Texas Medical Branch at Galveston, United States

    10 publications · 1K citations

    10

    h-index

  3. RP
    Robert P. Fuchs

    Centre National de la Recherche Scientifique, France

    9 publications · 457 citations

    9

    h-index

  4. LH
    Lajos Haracska

    Hungarian Academy of Sciences, Hungary

    8 publications · 981 citations

    8

    h-index

  5. JC
    Justin Courcelle

    Portland State University, United States

    7 publications · 299 citations

    7

    h-index

1–5 of 1.3K

Institutions

438

  1. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    59 publications

    2.9K citations

  2. The University of Texas Medical Branch at Galveston

    Galveston, United States

    10 h-index

    42 publications

    4.4K citations

  3. University of Sussex

    Brighton, United Kingdom

    9 h-index

    31 publications

    3.6K citations

  4. National Institutes of Health

    Bethesda, United States

    8 h-index

    34 publications

    4.3K citations

  5. Institute of Genetics

    Szeged, Hungary

    7 h-index

    35 publications

    3.2K citations

  6. University of Rochester

    Rochester, United States

    7 h-index

    21 publications

    3.7K citations

  7. Stanford University

    Stanford, United States

    7 h-index

    22 publications

    1.8K citations

  8. Cancer Research UK

    London, United Kingdom

    7 h-index

    19 publications

    2.9K citations

1–8 of 438

Venues

  1. Nucleic Acids Research

    43 publications · 2.3K citations

    28

    h-index

  2. Journal of Biological Chemistry

    JBC · 28 publications · 2.4K citations

    26

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 18 publications · 1.5K citations

    18

    h-index

  4. Molecular and Cellular Biology

    MCB · 13 publications · 1.4K citations

    13

    h-index

  5. Biochemistry

    11 publications · 488 citations

    11

    h-index

1–5