Concepedia

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

Marc A. Gavin, Sally R. M. Clarke, Ella Negrou, Alena M. Gallegos, Alexander Y. Rudensky

Nature Immunology · 2001 · 635 citations · 69 references

DOI

Concepts

References

69

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

, , +17

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.5K citations

, , +17

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

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CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

Angela M. Thornton, Ethan M. Shevach · The Journal of Experimental Medicine · 1998 · 2.6K citations · Full text

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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

Martha S. Jordan, Alina C. Boesteanu, Amy J. Reed et al. · Nature Immunology · 2001 · 1.6K citations

, , +15