Clive R. Wood

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

Cancer Immunosurveillance, Signal Transduction, Immunology +8

Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

Julia A. Brown, David M. Dorfman, Fengrong Ma et al. · The Journal of Immunology · 2003 · 954 citations

T-regulatory Cell, Immunology, Cell Death +17

PD‐1 inhibits T‐cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ

Kelly-Ann Sheppard, Lori Fitz, Julie M. Lee et al. · FEBS Letters · 2004 · 761 citations

PD-1:PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2

Laura Carter, Lynette A. Fouser, Jason Jussif et al. · European Journal of Immunology · 2002 · 665 citations

T-regulatory Cell, Immunology, Immune Regulation +16