T cell receptor antagonist peptides induce positive selection

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath, +2

Cell

T-regulatory CellImmunologyPositive SelectionAutoimmunityTolerance Induction +5

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

Angela M. Thornton, Ethan M. Shevach

The Journal of Experimental Medicine

T-regulatory CellImmunologyRegulatory T CellsCd4 T Cell ResponsesImmunotherapy +14

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

Takamune Takahashi, Yuhshi Kuniyasu, Masaaki Toda, +5

International Immunology

Normal Naive MiceT-regulatory CellCellular ImmunologyImmunologyImmunologic Mechanism +17

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.

M Asano, Masaaki Toda, N Sakaguchi, +1

The Journal of Experimental Medicine

Cd4+ CellsLymphocyte DevelopmentImmunologyNeonatal ThymectomyDevelopmental Abnormality +17

Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance

Misako Itoh, Takeshi Takahashi, Noriko Sakaguchi, +4

The Journal of Immunology

CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells

Elisabeth Suri‐Payer, Anna Z. Amar, Angela M. Thornton, +1

The Journal of Immunology

Lymphocyte DevelopmentT-regulatory CellImmunologyRegulatory T CellsCd4 T Cell Responses +15

Evidence for a differential avidity model of T cell selection in the thymus

Philip G. Ashton‐Rickardt, António Bandeira, Joseph R. Delaney, +4

Cell

Adaptive Immune SystemImmunologyAutoimmunityTolerance InductionT Cell Selection +6

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity

Hala S. Azzam, Alex Grinberg, Kin Lui, +3

The Journal of Experimental Medicine

Signal TransductionDevelopmental BiologyLymphocyte DevelopmentT-regulatory CellImmunology +13

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide

Eric Sebzda, Valerie A. Wallace, John P. Mayer, +3

Science

Transgenic TcrLymphocyte DevelopmentT-regulatory CellImmunologyImmunodominance +17

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor.

Jörg Kirberg, Alexandra Baron, Stephan M. Jakob, +3

The Journal of Experimental Medicine

HistocompatibilityTransgenic TcrLymphocyte DevelopmentImmunologyThymic Selection +18