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Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

Yumiko Shibouta, Yasuhiro Inada, M Ojima, Takeo Wada, Makoto Noda, Tsukasa Sanada, Keiji Kubo, Yasuhisa Kohara, Takehiko Naka, Kohei Nishikawa

Journal of Pharmacology and Experimental Therapeutics · 1993 · 213 citations · 0 references

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