M Ojima

Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

Yumiko Shibouta, Yasuhiro Inada, M Ojima et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 213 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Protective Effects of Candesartan Cilexetil (TCV-116) Against Stroke, Kidney Dysfunction and Cardiac Hypertrophy in Stroke-Prone Spontaneously Hypertensive Rats

Y Inada, Takao Wada, M Ojima et al. · Clinical and Experimental Hypertension · 1997 · 106 citations

Medicine, Pharmacology, Pharmacotherapy +17

Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats.

Yasuhiro Inada, Takeo Wada, Yumiko Shibouta et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 73 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Pharmacological profile of a novel nonpeptide angiotensin II subtype 1 receptor antagonist, TCV-116.

Kohei Nishikawa, Y Inada, Yumiko Shibouta et al. · PubMed · 1994 · 15 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Effects of delapril on stroke, kidney dysfunction and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats.

Y Inada, M Ojima, K. Itoh et al. · PubMed · 1995 · 10 citations

Pharmacy, Pharmacology, Pharmacotherapy +17