Concepedia

Yasuhisa Kohara

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Publications

9

Citations

1.2K

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9

Active since

1993

Affiliations

Takeda (Japan)(Current)

Yasuhisa Kohara is an author at Takeda (Japan) specializing in medicinal chemistry, receptor pharmacology, and pharmacology.

Publications per year

1993–2010

9

Publications

9

Synthesis and Angiotensin II Receptor Antagonistic Activities of Benzimidazole Derivatives Bearing Acidic Heterocycles as Novel Tetrazole Bioisosteres

Yasuhisa Kohara, Keiji Kubo, Eiko Imamiya et al. · Journal of Medicinal Chemistry · 1996 · 272 citations

, , +16

Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

Yumiko Shibouta, Yasuhiro Inada, M Ojima et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 213 citations

, , +13

In Vitro Antagonistic Properties of a New Angiotensin Type 1 Receptor Blocker, Azilsartan, in Receptor Binding and Function Studies

Mami Ojima, Hideki Igata, Masayuki Tanaka et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 150 citations

, , +17

Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of benzimidazolecarboxylic acids

Keiji Kubo, Yasuhisa Kohara, Eiko Imamiya et al. · Journal of Medicinal Chemistry · 1993 · 135 citations · Full text

, , +12

Nonpeptide angiotensin II receptor antagonists. Synthesis and biological activity of potential prodrugs of benzimidazole-7-carboxylic acids

Yasuhisa Kohara, Y. Yoshimura, Yumiko Shibouta et al. · Journal of Medicinal Chemistry · 1993 · 129 citations

, , +13

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