Concepedia

Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice

Mario Pende, Sara C. Kozma, Muriel Jaquet, Viola Oorschot, Rémy Burcelin, Y. Le Marchand‐Brustel, Judith Klumperman, Bernard Thorens, George Thomas

Nature · 2000 · 455 citations · 26 references

DOI

Concepts

References

26

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

, , +12

Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism

Kenta Hara, Kazuyoshi Yonezawa, Qing-Ping Weng et al. · Journal of Biological Chemistry · 1998 · 1.4K citations · Full text

, , +13

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

Eiichi Araki, Myra A. Lipes, Mary‐Elizabeth Patti et al. · Nature · 1994 · 1.3K citations

, , +17

Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

Rohit Kulkarni, Jens C. Brüning, Jonathon N. Winnay et al. · Cell · 1999 · 1.2K citations · Full text

, , +17

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe et al. · Nature · 1994 · 1.1K citations

, , +16