Jens C. Brüning

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Jens C. Brüning, Dinesh Gautam, Deborah J. Burks et al. · Science · 2000 · 2.2K citations

Insulin Receptors, Food Intake, Insulin Signaling +19

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

Eiichi Araki, Myra A. Lipes, Mary‐Elizabeth Patti et al. · Nature · 1994 · 1.2K citations

Molecular Physiology, Signal Transduction, Insulin Signalling +11

A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

Jens C. Brüning, M.Dodson Michael, Jonathon N. Winnay et al. · Molecular Cell · 1998 · 1.2K citations · Full text

Obesity, Metabolic Syndrome, Insulin Resistance +11

Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

Rohit Kulkarni, Jens C. Brüning, Jonathon N. Winnay et al. · Cell · 1999 · 1.1K citations · Full text

Insulin Resistance, Insulin Signaling, Molecular Physiology +13

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

Ashutosh Chaudhry, Robert Samstein, Piper M. Treuting et al. · Immunity · 2011 · 949 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +12