Kazuyuki Tobe

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

Insulin Resistance, Metabolic Syndrome, Obesity +11

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Toshimasa Yamauchi, Junji Kamon, Yusuke Ito et al. · Nature · 2003 · 3.1K citations

Obesity, Metabolic Syndrome, Biochemistry +7

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

Toshimasa Yamauchi, Yasunori Nio, Toshiyuki Maki et al. · Nature Medicine · 2007 · 1.4K citations

Metabolic Syndrome, Systems Biology, Signal Transduction +8

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

Naoto Kubota, Yasuo Terauchi, Hiroshi Miki et al. · Molecular Cell · 1999 · 1.4K citations · Full text

Insulin Resistance, Obesity, Metabolic Syndrome +10

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe et al. · Nature · 1994 · 1.1K citations

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +11