Naoto Kubota

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

Insulin Resistance, Metabolic Syndrome, Obesity +11

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

Toshimasa Yamauchi, Yasunori Nio, Toshiyuki Maki et al. · Nature Medicine · 2007 · 1.4K citations

Metabolic Syndrome, Systems Biology, Signal Transduction +8

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

Naoto Kubota, Yasuo Terauchi, Hiroshi Miki et al. · Molecular Cell · 1999 · 1.4K citations · Full text

Insulin Resistance, Obesity, Metabolic Syndrome +10

Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1

Masato Iwabu, Toshimasa Yamauchi, Miki Okada‐Iwabu et al. · Nature · 2010 · 946 citations

Metabolic Syndrome, Signal Transduction, Molecular Physiology +14

Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance

Nozomu Kamei, Kazuyuki Tobe, Ryo Suzuki et al. · Journal of Biological Chemistry · 2006 · 893 citations · Full text