New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

Yu‐Hua Tseng, Efi Kokkotou, Tim J. Schulz, +12

Nature

ObesityMetabolic SyndromeNew RoleBody CompositionDevelopmental Biology +12

Growth retardation and increased apoptosis in mice with homozygous disruption of the <i>akt1</i> gene

William S. Chen, Pei-Zhang Xu, Kathrin Gottlob, +9

Genes & Development

Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance

Nozomu Kamei, Kazuyuki Tobe, Ryo Suzuki, +21

Journal of Biological Chemistry

Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake

Naoto Kubota, Wataru Yano, Tetsuya Kubota, +24

Cell Metabolism

ObesityHypothalamic CircuitsMetabolic SyndromeNutritionGastrointestinal Peptide Hormone +12

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

Atsushi Tsuchida, Toshimasa Yamauchi, Yusuke Ito, +17

Journal of Biological Chemistry

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

Naoto Kubota, Kazuyuki Tobe, Yasuo Terauchi, +17

Diabetes

Insulin ReceptorInsulin SignalingCauses Type 2Metabolic SyndromeSkeletal Muscle +18

Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation

Yumiko Oishi, Ichiro Manabe, Kazuyuki Tobe, +12

Cell Metabolism

Transcriptional RegulationSignal TransductionKey RegulatorGeneticsAdipocyte Differentiation +6

Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis

Sudha B. Biddinger, Antonio Hernández‐Ono, Christian Rask‐Madsen, +11

Cell Metabolism

Insulin ResistanceMetabolic SyndromeInsulin SignalingHepatologyCardiovascular Disease +8

Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus

Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, +14

Journal of Clinical Investigation

Hypothalamic CircuitsInsulin SignalingGastrointestinal Peptide HormoneObesityMetabolic Syndrome +22

Discovery of T[CLC]e[/CLC]V Gamma Rays from SN 1006: Further Evidence for the Supernova Remnant Origin of Cosmic Rays

T. Tanimori, Y. Hayami, S. Kamei, +36

The Astrophysical Journal