Concepedia

The Linear Ubiquitin Chain Assembly Complex (LUBAC) Forms Part of the TNF-R1 Signalling Complex and Is Required for Effective TNF-Induced Gene Induction and Prevents TNF-Induced Apoptosis

Christoph H. Emmerich, Anna C. Schmukle, Tobias L. Haas, Björn Gerlach, Stefanie M. Cordier, Eva Rieser, Henning Walczak

Advances in experimental medicine and biology · 2010 · 14 citations · 34 references

DOI

Concepts

References

34

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

Ingrid E. Wertz, Karen O’Rourke, Honglin Zhou et al. · Nature · 2004 · 1.8K citations

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cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

Mathieu J.M. Bertrand, Snezana Milutinovic, Kathleen M. Dickson et al. · Molecular Cell · 2008 · 1.1K citations

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IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

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The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

Andrew Kovalenko, Christine Chable-Bessia, Giuseppina Cantarella et al. · Nature · 2003 · 1K citations

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