Concepedia

Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment

John Troutman, David L. Rick, Sharon B. Stuard, Jeffrey W. Fisher, Michael Bartels

Regulatory Toxicology and Pharmacology · 2015 · 38 citations · 21 references

DOI

Concepts

References

21

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

Friedrich K. Stephan, Irving H. Zucker · Proceedings of the National Academy of Sciences · 1972 · 2K citations

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Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

Barbara A. Wetmore, John F. Wambaugh, Stephen Ferguson et al. · Toxicological Sciences · 2011 · 411 citations

, , +14

The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

Jochem Louisse, Esther de Jong, Johannes J.M. van de Sandt et al. · Toxicological Sciences · 2010 · 153 citations · Full text

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Characterization and application of physiologically based pharmacokinetic models in risk assessment

Harrie Buist · TNO Repository · 2010 · 137 citations

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A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals

Thomas Peyret, Patrick Poulin, Kannan Krishnan · Toxicology and Applied Pharmacology · 2010 · 137 citations

, , +15