Johannes J.M. van de Sandt

Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

R. Kroes, A. G. Renwick, V.J. Feron et al. · Food and Chemical Toxicology · 2007 · 1.8K citations

Toxicological Concern, Medicine, Environmental Health +9

Current Status of Methods for Defining the Applicability Domain of (Quantitative) Structure-Activity Relationships

Tatiana I. Netzeva, Andrew Worth, Tom Aldenberg et al. · Alternatives to Laboratory Animals · 2005 · 800 citations

Preclinical Therapeutics, Engineering, Occupational Health Sciences +29

In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: a multi-centre comparison study

Johannes J.M. van de Sandt, Johan A. van Burgsteden, S. Cage et al. · Regulatory Toxicology and Pharmacology · 2004 · 223 citations

Vitro Predictions, Benzoic Acid, Medicine +6

The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

Jochem Louisse, Esther de Jong, Johannes J.M. van de Sandt et al. · Toxicological Sciences · 2010 · 153 citations · Full text

Predict Dose-response Curves, Systemic Toxicity, Physiologically-based Pharmacokinetic Modeling +18

A prevalidation study on in vitro tests for acute skin irritation

Julia H. Fentem, David Briggs, Christophe Chesné et al. · Toxicology in Vitro · 2001 · 152 citations

Vitro Tests, Allergy, Prevalidation Study +8