Jochem Louisse

The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

Jochem Louisse, Esther de Jong, Johannes J.M. van de Sandt et al. · Toxicological Sciences · 2010 · 153 citations · Full text

Predict Dose-response Curves, Systemic Toxicity, Physiologically-based Pharmacokinetic Modeling +18

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

Jochem Louisse, Deborah Rijkers, Geert Stoopen et al. · Archives of Toxicology · 2020 · 119 citations · Full text

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment

Umesh Chaudhari, Harshal Nemade, Vilas Wagh et al. · Archives of Toxicology · 2015 · 105 citations · Full text

Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds

Hequn Li, Bennard van Ravenzwaay, Ivonne M.C.M. Rietjens et al. · Archives of Toxicology · 2013 · 95 citations

Vitro Transport Model, Placental Transfer, Developmental Biology +8

Tutorial on physiologically based kinetic modeling in molecular nutrition and food research

Ivonne M.C.M. Rietjens, Jochem Louisse, Ans Punt · Molecular Nutrition & Food Research · 2011 · 85 citations · Full text