Deborah Rijkers

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

Jochem Louisse, Deborah Rijkers, Geert Stoopen et al. · Archives of Toxicology · 2020 · 130 citations · Full text

Life Sciences, Biochemistry, Toxicology +12

Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice

Brecht Attema, Aafke W. F. Janssen, Deborah Rijkers et al. · Molecular Metabolism · 2022 · 97 citations · Full text

Pharmacy, Endocrinology, Toxicology +17

Adverse Outcome Pathway-Driven Analysis of Liver Steatosis <i>in Vitro</i>: A Case Study with Cyproconazole

Claudia Luckert, Albert Braeuning, Georges de Sousa et al. · Chemical Research in Toxicology · 2018 · 77 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro

Dajana Lichtenstein, Claudia Luckert, Jimmy Alarcan et al. · Food and Chemical Toxicology · 2020 · 72 citations

Veterinary Medicine, Toxicology, Hepatotoxicology +15

Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)

Jochem Louisse, Luca Dellafiora, Jeroen J. M. W. van den Heuvel et al. · Archives of Toxicology · 2022 · 70 citations · Full text

Pharmacy, Pharmacokinetics, Toxicology +15