Aafke W. F. Janssen

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

Jochem Louisse, Deborah Rijkers, Geert Stoopen et al. · Archives of Toxicology · 2020 · 130 citations · Full text

Life Sciences, Biochemistry, Toxicology +12

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

Aafke W. F. Janssen, Tom Houben, Saeed Katiraei et al. · Journal of Lipid Research · 2017 · 118 citations · Full text

Life Sciences, Microbiology, Nutritional Sciences +17

Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Development

Anastasia Georgiadi, Yanan Wang, Rinke Stienstra et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 102 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

Aafke W. F. Janssen, Saeed Katiraei, Barbara Bartosinska et al. · Diabetologia · 2018 · 97 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice

Brecht Attema, Aafke W. F. Janssen, Deborah Rijkers et al. · Molecular Metabolism · 2022 · 97 citations · Full text

Pharmacy, Endocrinology, Toxicology +17