Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2

Jelmer J. van Zanden, Heleen M. Wortelboer, Sabina Bijlsma, +5

Biochemical Pharmacology

Medicinal ChemistryBiochemistryNatural SciencesMedicineRational Drug Design +8

Impact of nanoparticle surface functionalization on the protein corona and cellular adhesion, uptake and transport

Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, +5

Journal of Nanobiotechnology

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

Ans Punt, Andreas P. Freidig, Thierry Delatour, +5

Toxicology and Applied Pharmacology

Estragole BioactivationPharmacokinetic ModelingMedicineLipid PeroxidationPhysiology +7

Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

Ans Punt, Alicia Paini, Marelle G. Boersma, +6

Toxicological Sciences

Tutorial on physiologically based kinetic modeling in molecular nutrition and food research

Ivonne M.C.M. Rietjens, Jochem Louisse, Ans Punt

Molecular Nutrition & Food Research

Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes

S.M.F. Jeurissen, Ans Punt, Marelle G. Boersma, +6

Chemical Research in Toxicology

Related AlkenylbenzenesAldehyde DehydrogenaseBiochemistryEstragole 1'-HydroxylationMedicine +11

Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose–response curves for developmental toxicity of phenol in rat and human

Marije Strikwold, Bert Spenkelink, R.A. Woutersen, +2

Archives of Toxicology

Developmental BiologyPharmacokinetic ModelingPredictive ToxicologyDevelopmental ToxicologyPhysiology +12

A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

Alicia Paini, Ans Punt, Florian Viton, +6

Toxicology and Applied Pharmacology

Molecular PharmacologyBiochemistryMedicineLiver PhysiologyEstragole Dna Binding +4

Tandem Mass Spectrometry Analysis of <i>N</i>²-(<i>trans</i>-Isoestragol-3‘-yl)-2‘-deoxyguanosine as a Strategy to Study Species Differences in Sulfotransferase Conversion of the Proximate Carcinogen 1‘-Hydroxyestragole

Ans Punt, Thierry Delatour, Gabriele Scholz, +3

Chemical Research in Toxicology

Biological Mass SpectrometryMetabolomic ProfilingSecondary MetaboliteSulfotransferase ConversionOxidative Stress +23

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols

Marije Strikwold, Bert Spenkelink, Laura H.J. de Haan, +3

Archives of Toxicology