Chlorpyrifos: Pharmacokinetics in human volunteers

R.J. Nolan, David L. Rick, N. L. Freshour, +1

Toxicology and Applied Pharmacology

Human VolunteersPharmacologyToxicologyPharmacotherapyMedicine +2

Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing – An integrated approach without additional animal use

Shakil A. Saghir, Michael Bartels, David L. Rick, +8

Regulatory Toxicology and Pharmacology

EcotoxicityIntegrated ApproachMedicineEnvironmental HealthToxicology Testing +8

Reconstruction of Exposure to<i>m</i>-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

Kevin McNally, Richard Cotton, John Cocker, +5

Journal of Toxicology

The Effect of Plasma Lipids on the Pharmacokinetics of Chlorpyrifos and the Impact on Interpretation of Blood Biomonitoring Data

Ezra R. Lowe, Torka S. Poet, David L. Rick, +4

Toxicological Sciences

Plasma PartitioningPlasma LipidsPlasma Lipid LevelsToxicologyAnalytical Chemistry +14

Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment

John Troutman, David L. Rick, Sharon B. Stuard, +2

Regulatory Toxicology and Pharmacology

Pharmacokinetic ModelingPharmacological StudyMedicinePhysiologyToxicology +9

Mechanism of Ethylbenzene-Induced Mouse-Specific Lung Tumor: Metabolism of Ethylbenzene by Rat, Mouse, and Human Liver and Lung Microsomes

Shakil A. Saghir, David L. Rick, Erin L. McClymont, +3

Toxicological Sciences

Simultaneous quantitation of testosterone and estradiol in human cell line (H295R) by liquid chromatography/positive atmospheric pressure photoionization tandem mass spectrometry

F. Zhang, David L. Rick, L. Kan, +4

Rapid Communications in Mass Spectrometry

Possible InteractionGynecologyFemale Reproductive FunctionEnvironmental ConcernBioanalysis +17

Development of PK- and PBPK-based modeling tools for derivation of biomonitoring guidance values

M. Bartels, David L. Rick, Ezra R. Lowe, +6

Computer Methods and Programs in Biomedicine

EngineeringPbpk-based Modeling ToolsGuidance ValuesBioenergeticsCalibration +7

Absorption, distribution, metabolism and excretion of intravenously and dermally administered triethanolamine in mice

William T. Stott, John M. Waechter, David L. Rick, +1

Food and Chemical Toxicology

MedicinePhysiologyForensic ToxicologyToxicologyMetabolism +2

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Shakil A. Saghir, Fagen Zhang, David L. Rick, +3

Regulatory Toxicology and Pharmacology

Covalent BindingTumor MicroenvironmentOncogenic AgentMedicinePulmonary Pharmacology +8