Concepedia

Pharmacokinetic Simulation

Pharmacokinetic Simulation is a computational modeling technique that uses mathematically specified pharmacokinetic models and associated parameter distributions to predict the time course of drug concentrations and related exposure metrics in individuals or populations under defined dosing and physiological scenarios.

2.9K

Publications

134.7K

Citations

10K

Authors

2.6K

Institutions

Publications per year

2017–2026

921

Variants

Simulation In Pharmacokinetics

Parents

Children

Publications

2.9K

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

, , +15

Clinical pharmacokinetics; concepts and applications

General Pharmacology The Vascular System · 1989 · 2.2K citations

, , +12

Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Trudy Rodgers, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2006 · 940 citations

, , +11

Basic Concepts in Population Modeling, Simulation, and Model‐Based Drug Development—Part 2: Introduction to Pharmacokinetic Modeling Methods

DR Mould · CPT Pharmacometrics & Systems Pharmacology · 2013 · 880 citations · Full text

, , +17

Context-sensitive Half-time in Multicompartment

M.A. Hughes, Peter S. A. Glass, James Jacobs · Anesthesiology · 1992 · 799 citations · Full text

, , +15

1–5 of 2.9K

Authors

10K

  1. GL
    George L. Drusano

    Albany Medical Center Hospital, United States

    34 publications · 2.3K citations

    26

    h-index

  2. JA
    Jason A. Roberts

    The University of Queensland, Australia

    35 publications · 1.7K citations

    25

    h-index

  3. AR
    Amin Rostami‐Hodjegan

    University of Manchester, United Kingdom

    30 publications · 2.3K citations

    24

    h-index

  4. MJ
    Masoud Jamei

    Simcyp (United Kingdom), United Kingdom

    28 publications · 1.6K citations

    23

    h-index

  5. ME
    Melvin E. Andersen

    The Hamner Institutes for Health Sciences, United States

    32 publications · 2.4K citations

    23

    h-index

1–5 of 10K

Institutions

2.6K

  1. University of Manchester

    Manchester, United Kingdom

    39 h-index

    162 publications

    11.4K citations

  2. Inserm

    Paris, France

    36 h-index

    293 publications

    11.2K citations

  3. Pfizer (United States)

    New York, United States

    34 h-index

    184 publications

    11.8K citations

  4. Simcyp (United Kingdom)

    Sheffield, United Kingdom

    33 h-index

    222 publications

    12.7K citations

  5. The University of Queensland

    Brisbane, Australia

    33 h-index

    166 publications

    8.1K citations

  6. University of California, San Francisco

    San Francisco, United States

    32 h-index

    113 publications

    7.9K citations

  7. Roche (Switzerland)

    Basel, Switzerland

    32 h-index

    155 publications

    10.6K citations

  8. Uppsala University

    Uppsala, Sweden

    31 h-index

    151 publications

    8.6K citations

1–8 of 2.6K

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 159 publications · 7.9K citations

    52

    h-index

  2. Journal of Pharmaceutical Sciences

    115 publications · 7K citations

    43

    h-index

  3. CPT Pharmacometrics & Systems Pharmacology

    PSP · 94 publications · 7K citations

    37

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 70 publications · 4.1K citations

    36

    h-index

  5. Journal of Antimicrobial Chemotherapy

    JAC · 99 publications · 3.7K citations

    35

    h-index

1–5