Masoud Jamei

Physiologically based mechanistic modelling to predict complex drug–drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut—The effect of diltiazem on the time-course of exposure to triazolam

Karen Rowland Yeo, Masoud Jamei, Jiansong Yang et al. · European Journal of Pharmaceutical Sciences · 2009 · 185 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

Adam S. Darwich, Sibylle Neuhoff, Masoud Jamei et al. · Current Drug Metabolism · 2010 · 182 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

Masoud Jamei, F. Bajot, Sibylle Neuhoff et al. · Clinical Pharmacokinetics · 2013 · 161 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Variability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision Criteria

Joe Bentz, Michael O′Connor, Dallas Bednarczyk et al. · Drug Metabolism and Disposition · 2013 · 150 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +9

A pregnancy physiologically based pharmacokinetic (p‐<scp>PBPK</scp>) model for disposition of drugs metabolized by <scp>CYP1A2</scp>, <scp>CYP2D6</scp> and <scp>CYP3A4</scp>

Lu Gaohua, Khaled Abduljalil, Masoud Jamei et al. · British Journal of Clinical Pharmacology · 2012 · 120 citations

Pharmacy, Pharmacokinetics, Pharmacology +17