Jiansong Yang

Physiologically based mechanistic modelling to predict complex drug–drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut—The effect of diltiazem on the time-course of exposure to triazolam

Karen Rowland Yeo, Masoud Jamei, Jiansong Yang et al. · European Journal of Pharmaceutical Sciences · 2009 · 185 citations

Systems Pharmacology, Drug Interactions, Molecular Pharmacology +11

Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA

Jiansong Yang, Masoud Jamei, Amir Heydari et al. · Journal of Psychopharmacology · 2006 · 88 citations

Mechanism-based Inhibition, Pharmacological Study, Biochemistry +13

Physiologically-based Kinetic Modelling (PBK Modelling): Meeting the 3Rs Agenda

Michel Bouvier d’Yvoire, Pilar Prieto, Bas J. Blaauboer et al. · Alternatives to Laboratory Animals · 2007 · 73 citations

Physiology, Ecvam Workshop 63, Physiologically-based Kinetic Modelling +12

The Consequences of 3,4-Methylenedioxymethamphetamine Induced CYP2D6 Inhibition in Humans

Brian O’Mathúna, Amin Rostami‐Hodjegan, Jiansong Yang et al. · Journal of Clinical Psychopharmacology · 2008 · 65 citations

Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study

Li Liu, Yunli Yu, Jiansong Yang et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2010 · 64 citations

Beneficial Metabolic Effects, Diabetes Management, Biochemistry +10