Sibylle Neuhoff - Concepedia

Author

Sibylle Neuhoff

Simcyp (United Kingdom)ORCID

Also Known As

Hartauer, Mattie, Neuhoff, Sibylle, S Neuhoff, S. Neuhoff, Sibylle Neuhoff

113

Publications

4.1K

Citations

H-Index

Concepts

All Affiliations

Simcyp (United Kingdom)University of Manchester Uppsala University AstraZeneca (Sweden)AstraZeneca (United Kingdom)

About

Sibylle Neuhoff is an author at Simcyp (United Kingdom) specializing in medicine, pharmacology, and pharmacokinetics.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	13	911
2	Biochemistry	7	7	571
3	Natural Sciences	4	4	456
4	Health Sciences	3	3	195
5	Cell Biology	2	2	96

Sibylle Neuhoff

Publications

2.5K

Citations

H-Index

Page 1

	Year	Citations
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA method Alex Avdeef, Per Artursson, Sibylle Neuhoff, European Journal of Pharmaceutical Sciences Medicinal ChemistryBiochemistryCaco-2 PermeabilityMedicineNatural Sciences	2005	213
pH-Dependent Bidirectional Transport of Weakly Basic Drugs Across Caco-2 Monolayers: Implications for Drug–Drug Interactions Sibylle Neuhoff, Anna‐Lena Ungell, Ismael Zamora, Pharmaceutical Research	2003	207
Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the &#x201C;Advanced Dissolution, Absorption, Metabolism (ADAM)&#x201D; Model Adam S. Darwich, Sibylle Neuhoff, Masoud Jamei, Current Drug Metabolism	2010	178
A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine Masoud Jamei, F. Bajot, Sibylle Neuhoff, Clinical Pharmacokinetics	2013	160
Variability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision Criteria Joe Bentz, Michael O′Connor, Dallas Bednarczyk, Drug Metabolism and Disposition	2013	147
pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers Sibylle Neuhoff, Anna‐Lena Ungell, Ismael Zamora, European Journal of Pharmaceutical Sciences Molecular PharmacologyAcidic DrugsProteinlipid InteractionBiochemistryCaco-2 Cell Monolayers	2005	147
Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions Howard Burt, Sibylle Neuhoff, Lisa M. Almond, European Journal of Pharmaceutical Sciences	2016	118
Proteomic Quantification of Human Blood–Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients Zubida M. Al‐Majdoub, Hajar Al Feteisi, Brahim Achour, Molecular Pharmaceutics Abc TransportersNeurochemical BiomarkersCerebral Vascular RegulationNeuroinflammationAlzheimer's Disease	2019	115
In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Drug Metabolism and Disposition	2015	75
Application of a Physiologically Based Pharmacokinetic Model to Predict <i>OATP1B1</i>‐Related Variability in Pharmacodynamics of Rosuvastatin RH Rose, Sibylle Neuhoff, Khaled Abduljalil, CPT Pharmacometrics & Systems Pharmacology Pd ResponsePharmacotherapyPhysiologically-based Pharmacokinetic ModelingPharmacodynamic ModelingMolecular Pharmacology	2014	74

Page 1