Lu Gaohua

A pregnancy physiologically based pharmacokinetic (p‐<scp>PBPK</scp>) model for disposition of drugs metabolized by <scp>CYP1A2</scp>, <scp>CYP2D6</scp> and <scp>CYP3A4</scp>

Lu Gaohua, Khaled Abduljalil, Masoud Jamei et al. · British Journal of Clinical Pharmacology · 2012 · 119 citations

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

Howard Burt, Sibylle Neuhoff, Lisa M. Almond et al. · European Journal of Pharmaceutical Sciences · 2016 · 118 citations · Full text

Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses

Zufei Zhang, Marjorie Z. Imperial, Gabriela I. Patilea‐Vrana et al. · Drug Metabolism and Disposition · 2017 · 98 citations · Full text

Development of a Multicompartment Permeability‐Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs

Lu Gaohua, J. R. Wedagedera, Lisa M. Almond et al. · CPT Pharmacometrics & Systems Pharmacology · 2015 · 83 citations · Full text

Lung Deposition, Pharmacokinetic Modeling, Antibiotics +15

Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data

Lu Gaohua, Sibylle Neuhoff, Trevor N. Johnson et al. · Drug Metabolism and Pharmacokinetics · 2016 · 74 citations · Full text