Concepedia

Author

Howard Burt

Simcyp (United Kingdom)

Also Known As

H BURT, H.J. Burt, Howard Burt, Howard J Burt, Howard J. Burt

25

Publications

834

Citations

13

H-Index

25

Concepts

All Affiliations

Simcyp (United Kingdom)University of ManchesterMerck Serono (Switzerland)Swiss Tropical and Public Health InstituteUniversity of Basel
HB

About

Howard Burt is an author at Simcyp (United Kingdom) specializing in pharmacology, medicine, and pharmacokinetic modeling.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

103

2

Natural Sciences

1

1

43

3

Biochemistry

1

1

43

4

Endocrinology

1

1

19

5

Nutrition

1

1

23

Howard Burt

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9

Publications

470

Citations

9

H-Index

YearCitations

PREDICTION OF TIME-DEPENDENT CYP3A4 DRUG-DRUG INTERACTIONS: IMPACT OF ENZYME DEGRADATION, PARALLEL ELIMINATION PATHWAYS, AND INTESTINAL INHIBITION

Aleksandra Galetin, Howard Burt, Laura E. Gibbons,

Drug Metabolism and Disposition

2005

161

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

Howard Burt, Sibylle Neuhoff, Lisa M. Almond,

European Journal of Pharmaceutical Sciences

2016

118

Identification and Optimization of an Aminoalcohol-Carbazole Series with Antimalarial Properties

Jérôme Molette, Julie Routier, Nada Abla,

ACS Medicinal Chemistry Letters

2013

43

IC<sub>50</sub>-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4

Howard Burt, Aleksandra Galetin, J. Brian Houston

Xenobiotica

2010

43

More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter‐Mediated Clearances

Ariane Emami Riedmaier, Howard Burt, Khaled Abduljalil,

The Journal of Clinical Pharmacology

2016

25

Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale

Peter L. Bonate, Tianli Wang, Paul Passier,

Journal of Pharmacokinetics and Pharmacodynamics

2018

23

Progress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4

Howard Burt, Henry Pertinez, Carolina Säll,

Drug Metabolism and Disposition

2012

20

Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency

Jennifer J. Bonner, Howard Burt, Trevor N. Johnson,

European Journal of Pharmaceutical Sciences

2021

19

Development and application of a PBPK modeling strategy to support antimalarial drug development

Nada Abla, Eleanor Howgate, Karen Rowland Yeo,

CPT Pharmacometrics & Systems Pharmacology

2023

18

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