Concepedia
Statistics
Publications
70
Citations
5.2K
H-Index
38
Active since
1972
Affiliations
University of Manchester(Current)
GlaxoSmithKline (United Kingdom)
University at Buffalo, State University of New York
Manchester Academic Health Science Centre
J. Brian Houston is an author at University of Manchester specializing in pharmacology, pharmacokinetics, and pharmacy.
Publications per year
1972–2023
The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions
R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 437 citations
Pharmacy, Pharmacokinetics, Pharmacology +17
Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data
Michael Gertz, Anthony Harrison, J. Brian Houston et al. · Drug Metabolism and Disposition · 2010 · 299 citations
Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
Hannah M. Jones, Hugh A. Barton, Yurong Lai et al. · Drug Metabolism and Disposition · 2012 · 242 citations
Pharmacy, Pharmacokinetics, Pharmacology +16
Critique of the Two-Fold Measure of Prediction Success for Ratios: Application for the Assessment of Drug-Drug Interactions
Eleanor J. Guest, Leon Aarons, J. Brian Houston et al. · Drug Metabolism and Disposition · 2010 · 191 citations
Pharmacy, Pharmacokinetics, Pharmacology +15
SUBSTRATE DEPLETION APPROACH FOR DETERMINING IN VITRO METABOLIC CLEARANCE: TIME DEPENDENCIES IN HEPATOCYTE AND MICROSOMAL INCUBATIONS
Hannah M. Jones, J. Brian Houston · Drug Metabolism and Disposition · 2004 · 184 citations
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