Concepedia

The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions

R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan, Emily A. Gaman, J. Brian Houston, Larry M. Tremaine

Journal of Pharmacology and Experimental Therapeutics · 2005 · 437 citations · 128 references

DOI

Concepts

References

128

THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · Drug Metabolism and Disposition · 2003 · 784 citations

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VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES

Robert L. Walsky, R. Scott Obach · Drug Metabolism and Disposition · 2004 · 504 citations

, , +15

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin*

Jack Gorski, D. I. Jones, B HAEHNERDANIELS et al. · Clinical Pharmacology & Therapeutics · 1998 · 411 citations

, , +14

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance

M.G. Scordo · Clinical Pharmacology & Therapeutics · 2002 · 344 citations

, , +17

CYP3A4 drug interactions: correlation of 10 <i>in vitro</i> probe substrates

Kenworthy, Bloomer, Houston · British Journal of Clinical Pharmacology · 1999 · 337 citations · Full text

, , +17