Drug Interactions

Drug interaction is an adverse drug reaction resulting from the modification of one drug's pharmacokinetic or pharmacodynamic effects by a concurrently administered drug.

6.1K

Publications

285K

Citations

21.7K

Authors

4.6K

Institutions

Publications per year

2017–2026

1.2K

Variants

Drug Interaction

Parents

Veterinary Pharmacology

Children

Absorption InteractionsCytochrome P450 InteractionsDistribution InteractionsDrug-disease InteractionsDrug-food InteractionsDrug-herb InteractionsDrug-nutrient InteractionsEnzyme InductionEnzyme InhibitionExcretion Interactions

Publications

6.1K

Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects

William E. Evans, Howard L. McLeod · New England Journal of Medicine · 2003 · 1.8K citations

Medicine, Genetics, Pharmacology +17

Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin

Francesca Catella-Lawson, Muredach P. Reilly, Shiv Kapoor et al. · New England Journal of Medicine · 2001 · 1.4K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Modeling polypharmacy side effects with graph convolutional networks

Marinka Žitnik, Monica Agrawal, Jure Leskovec · Bioinformatics · 2018 · 1.4K citations · Full text

Life Sciences, Bioinformatics, Pharmacology +17

Drug Target Identification Using Side-Effect Similarity

Mónica Campillos, Michael Kuhn, Anne‐Claude Gavin et al. · Science · 2008 · 1.2K citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

The problem of synergism and antagonism of combined drugs.

S. Loewe · PubMed · 1953 · 984 citations

Medicine, Pharmacology, Pharmacotherapy +9

1–5 of 6.1K

Authors

21.7K

PJ
Pertti J. Neuvonen
University of Helsinki, Finland
38 publications · 2.9K citations
29
h-index
WE
Walter E. Haefeli
Heidelberg University, Germany
30 publications · 1.6K citations
21
h-index
DC
Daniel C. Malone
University of Arizona, United States
34 publications · 1.8K citations
20
h-index
KT
Klaus T. Olkkola
University of Helsinki, Finland
21 publications · 1.8K citations
19
h-index
DJ
David J. Greenblatt
Tufts University, United States
23 publications · 1.2K citations
19
h-index

1–5 of 21.7K

Institutions

4.6K

1–8 of 4.6K

Venues

PubMed
Repository · 539 publications · 20K citations
62
h-index
Clinical Pharmacology & Therapeutics
CPT · 141 publications · 9.1K citations
56
h-index
European Journal of Clinical Pharmacology
176 publications · 7.7K citations
48
h-index
Drug Metabolism and Disposition
88 publications · 6.6K citations
46
h-index
Antimicrobial Agents and Chemotherapy
AAC · 102 publications · 6K citations
44
h-index

1–5

See also Drug Interactions
Mechanisms	Pharmacokinetic Drug Interactions Pharmacodynamic Drug Interactions Drug-drug Interactions Affecting Metabolism Drug Transport In Tissues Elimination Interaction Modeling Drug Distribution Regulation
Management Strategies	Therapeutic Drug Monitoring Machine Learning Clinical Decision Support Systems Patient Monitoring Dose Adjustment Criteria Drug Sequencing
Clinical Effects	Adverse Drug Reactions Bleeding
Detection Methods	Clinical Trials Pharmacokinetic Modeling Machine Learning Deep Learning Text Mining Natural Language Processing Post-marketing Surveillance Semi-supervised Learning Supervised Learning Knowledge Graphs Graph Neural Networks Naive Bayes Drug-target Similarity Networks Label Propagation Large Language Models Drug-drug Interaction Checking Support Vector Machines Regression