Karthik Venkatakrishnan

Author

Millennium Engineering and Integration (United States)ORCID

Also Known As

K S Venkatakrishnan, K VENKATAKRISHNAN, K Venkatakrishnan, K. S. Venkatakrishnan, K. Venkatakrishnan, K.S. Venkatakrishnan, Karthik Venkatakrishnan, Neeraj Gupta

323

Publications

9.4K

Citations

H-Index

133

Concepts

All Affiliations

Millennium Engineering and Integration (United States)Takeda (United States)Takeda (Japan)Tufts University Pfizer (United States)

About

Karthik Venkatakrishnan is an author at Millennium Engineering and Integration (United States) specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	24	34	1.5K
2	Engineering	8	8	291
3	Natural Sciences	3	3	200
4	Arts	1	1	12
5	Health Sciences	1	1	95

Karthik Venkatakrishnan

114

Publications

7.2K

Citations

H-Index

Page 1

	Year	Citations
Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan Drug Metabolism and Disposition	2006	454
THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL Angela C. Doran, R. Scott Obach, Bill J. Smith, Drug Metabolism and Disposition	2004	440
The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan, Journal of Pharmacology and Experimental Therapeutics	2005	434
CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants L M Hesse, Karthik Venkatakrishnan, Michael H. Court, Drug Metabolism and Disposition	2000	397
Apparent Mechanism-based Inhibition of Human CYP2D6 in Vitro by Paroxetine: Comparison with Fluoxetine and Quinidine Kirk Bertelsen, Karthik Venkatakrishnan, Lisa L. von Moltke, Drug Metabolism and Disposition	2003	270
Cytochrome P-450 2B6 Is Responsible for Interindividual Variability of Propofol Hydroxylation by Human Liver Microsomes Michael H. Court, Su Duan, Leah M. Hesse, Anesthesiology	2001	208
Comparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the Approaches Karthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Drug Metabolism and Disposition	2000	197
Phase I Study of Aurora A Kinase Inhibitor MLN8237 in Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics, and Bioavailability of Two Oral Formulations Elizabeth Claire Dees, Roger B. Cohen, Margaret von Mehren, Clinical Cancer Research	2012	156
Five Distinct Human Cytochromes Mediate Amitriptyline N‐Demethylation<i>In Vitro</i>: Dominance of CYP 2C19 and 3A4 Karthik Venkatakrishnan, David J. Greenblatt, Lisa L. von Moltke, The Journal of Clinical Pharmacology	1998	155
Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors Andrés Cervantes, Élena Elez, Desamparados Roda, Clinical Cancer Research	2012	150

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