Angela C. Doran

THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL

Angela C. Doran, R. Scott Obach, Bill J. Smith et al. · Drug Metabolism and Disposition · 2004 · 440 citations

Medicine, Pharmacokinetics, Pharmacology +16

Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding

Xingrong Liu, Bill J. Smith, Cuiping Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 184 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Selective Inhibition of Casein Kinase 1ϵ Minimally Alters Circadian Clock Period

Kevin M. Walton, Katherine Fisher, David M. Rubitski et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 181 citations

Nursing, Pharmacology, Cell Signaling +11

Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration

Xingrong Liu, Bill J. Smith, Cuiping Chen et al. · Drug Metabolism and Disposition · 2006 · 161 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Modeling and Validating Chronic Pharmacological Manipulation of Circadian Rhythms

M. Marconi, Douglas E. Wood, Angela C. Doran et al. · CPT Pharmacometrics & Systems Pharmacology · 2013 · 51 citations · Full text

Nursing, Pharmacology, Circadian Rhythms +15