Concepedia
Drug Metabolism and Disposition · 2006 · 160 citations · 20 references
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Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Temozolomide in Malignant Glioma Patients
Sandrine Ostermann, Chantal Csajka, Thierry Buclin et al. · Clinical Cancer Research · 2004 · 500 citations · Full text
THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL
Angela C. Doran, R. Scott Obach, Bill J. Smith et al. · Drug Metabolism and Disposition · 2004 · 440 citations
DEVELOPMENT OF A COMPUTATIONAL APPROACH TO PREDICT BLOOD-BRAIN BARRIER PERMEABILITY
Xingrong Liu, Meihua Tu, Rebecca S. Kelly et al. · Drug Metabolism and Disposition · 2004 · 237 citations
RELATIONSHIP BETWEEN EXPOSURE AND NONSPECIFIC BINDING OF THIRTY-THREE CENTRAL NERVOUS SYSTEM DRUGS IN MICE
Tristan S. Maurer, Demetria B. DeBartolo, David A. Tess et al. · Drug Metabolism and Disposition · 2004 · 215 citations
Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding
Xingrong Liu, Bill J. Smith, Cuiping Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 182 citations