Xingrong Liu

Ser ¹²⁹² Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Zejuan Sheng, Shuo Zhang, Daisy Bustos et al. · Science Translational Medicine · 2012 · 375 citations

Medicine, Cell Biology, Pharmacology +10

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Reina N. Fuji, Michael Flagella, Miriam Baca et al. · Science Translational Medicine · 2015 · 370 citations

Pharmacy, Pharmacology, Toxicology +13

Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding

Xingrong Liu, Bill J. Smith, Cuiping Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 184 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease

Claire E. Le Pichon, William J. Meilandt, Sara L. Domínguez et al. · Science Translational Medicine · 2017 · 165 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors

Anthony A. Estrada, Xingrong Liu, Charles Baker‐Glenn et al. · Journal of Medicinal Chemistry · 2012 · 164 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17