Reina N. Fuji

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Reina N. Fuji, Michael Flagella, Miriam Baca et al. · Science Translational Medicine · 2015 · 363 citations

Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

Jagath R. Junutula, Kelly M. Flagella, Richard Graham et al. · Clinical Cancer Research · 2010 · 289 citations

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

Jessica A. Couch, Yang Yu, Yin Zhang et al. · Science Translational Medicine · 2013 · 259 citations

Immunology, Immunotherapy, Cerebral Vascular Regulation +17

Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

Andrew G. Polson, Jill Calemine-Fenaux, Pamela Chan et al. · Cancer Research · 2009 · 247 citations

Immunology, Chemical Linkers, Immunotherapeutics +17