Jessica A. Couch

Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

Yang Yu, Jasvinder K. Atwal, Yin Zhang et al. · Science Translational Medicine · 2014 · 369 citations

Pharmacy, Neuroscience, Pharmacology +17

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

Megan Lo, Hok Seon Kim, Raymond K. Tong et al. · Journal of Biological Chemistry · 2017 · 330 citations · Full text

Pharmacy, Immunology, Antibody Engineering +16

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

Jessica A. Couch, Yang Yu, Yin Zhang et al. · Science Translational Medicine · 2013 · 266 citations

Pharmacy, Immunology, Pharmacology +17

Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation

Kathryn Chapman, Henry H. Holzgrefe, Lauren E. Black et al. · Regulatory Toxicology and Pharmacology · 2013 · 135 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Enhanced activation of reward mediating prefrontal regions in response to food stimuli in Prader-Willi syndrome

J. L Miller, G. Andrew James, Anthony P. Goldstone et al. · Journal of Neurology Neurosurgery & Psychiatry · 2006 · 117 citations · Full text

Medicine, Neuroscience, Psychology +17