Concepedia

Lauren E. Black

LE

8

Publications

1.2K

Citations

8

H-Index

1993

Active since

Affiliations

Charles River Laboratories (United States)(Current)

United States Food and Drug Administration

National Centre for the Replacement Refinement and Reduction of Animals in Research

Lauren E. Black is an author at Charles River Laboratories (United States) specializing in medicine, pharmacology, and toxicology.

ORCID

Top concepts

Publications per year

1993–2023

8

Publications

8

Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease

Jin‐Kuk Kim, Chunguang Hu, Christelle Moufawad El Achkar et al. · New England Journal of Medicine · 2019 · 772 citations · Full text

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Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation

Kathryn Chapman, Henry H. Holzgrefe, Lauren E. Black et al. · Regulatory Toxicology and Pharmacology · 2013 · 132 citations · Full text

, , +20

An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the <i>UBE3A-AS</i> transcript

Scott V. Dindot, Sarah Christian, William J. Murphy et al. · Science Translational Medicine · 2023 · 80 citations

The design of chronic toxicology studies of monoclonal antibodies: Implications for the reduction in use of non-human primates

Kathryn Chapman, Laura Andrews, Jeffrey J. Bajramović et al. · Regulatory Toxicology and Pharmacology · 2011 · 67 citations

, , +12

Regulatory Considerations for Oligonucleotide Drugs: Updated Recommendations for Pharmacology and Toxicology Studies

Lauren E. Black, James G. Farrelly, JOY A. CAVAGNARO et al. · Antisense Research and Development · 1994 · 61 citations

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