Concepedia

The design of chronic toxicology studies of monoclonal antibodies: Implications for the reduction in use of non-human primates

Kathryn Chapman, Laura Andrews, Jeffrey J. Bajramović, Paul Baldrick, Lauren E. Black, Christopher Bowman, Lorrene A. Buckley, Lee Coney, Jessica A. Couch, Alice M. Dempster,

Regulatory Toxicology and Pharmacology · 2011 · 67 citations · 5 references

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5

Directive 2010/63/EU of the European Parliament and Council of 22 September on the protection of animals used for scientific purposes

Eu · 2010 · 1.3K citations

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Spending on new drug development1

Christopher Adams, Van V. Brantner · Health Economics · 2009 · 274 citations

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Preclinical development of monoclonal antibodies

Kathryn Chapman, Nick Pullen, Lee Coney et al. · mAbs · 2009 · 97 citations · Full text

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Statistics of Scientific Procedures on living animals, Great Britain 2011

E Carter · Animal Welfare · 2012 · 92 citations

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Safety evaluation of biological drugs: What are toxicology studies in primates telling us?

Paul Baldrick · Regulatory Toxicology and Pharmacology · 2010 · 47 citations

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