Anthony A. Estrada

Ser ¹²⁹² Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations

Zejuan Sheng, Shuo Zhang, Daisy Bustos et al. · Science Translational Medicine · 2012 · 375 citations

Medicine, Cell Biology, Pharmacology +10

A Mild and Selective Method for the Hydrolysis of Esters with Trimethyltin Hydroxide

K. C. Nicolaou, Anthony A. Estrada, Mark Zak et al. · Angewandte Chemie International Edition · 2005 · 374 citations

Engineering, Chemical Engineering, Enzymology +3

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Reina N. Fuji, Michael Flagella, Miriam Baca et al. · Science Translational Medicine · 2015 · 370 citations

Pharmacy, Pharmacology, Toxicology +13

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease

Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry et al. · Science Translational Medicine · 2022 · 252 citations

Life Sciences, Neuroscience, Pharmacology +17

Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors

Anthony A. Estrada, Xingrong Liu, Charles Baker‐Glenn et al. · Journal of Medicinal Chemistry · 2012 · 164 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17