Bill J. Smith

THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL

Angela C. Doran, R. Scott Obach, Bill J. Smith et al. · Drug Metabolism and Disposition · 2004 · 440 citations

Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches

Natilie Hosea, Wendy T. Collard, Susan Cole et al. · The Journal of Clinical Pharmacology · 2009 · 292 citations

DEVELOPMENT OF A COMPUTATIONAL APPROACH TO PREDICT BLOOD-BRAIN BARRIER PERMEABILITY

Xingrong Liu, Meihua Tu, Rebecca S. Kelly et al. · Drug Metabolism and Disposition · 2004 · 237 citations

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human

Mark S. Warren, Noa Zerangue, Katie Woodford et al. · Pharmacological Research · 2009 · 234 citations

Abc Transporters, Glioma, Neurophysiology +10

Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding

Xingrong Liu, Bill J. Smith, Cuiping Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 182 citations