Natilie Hosea - Concepedia

Author

Natilie Hosea

Pfizer (United States)

Also Known As

N. Hosea, Natilie A Hosea, Natilie A. Hosea, Natilie Hosea

Publications

2.5K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Pfizer (United Kingdom)Vanderbilt University University of California San Diego University at Buffalo, State University of New York

About

Natilie Hosea is an author at Pfizer (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	320
2	Natural Sciences	5	5	251
3	Biochemistry	5	5	251
4	Chemical Biology	2	2	81
5	Cell Biology	1	1	10

Natilie Hosea

Publications

2.3K

Citations

H-Index

Page 1

	Year	Citations
THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL Angela C. Doran, R. Scott Obach, Bill J. Smith, Drug Metabolism and Disposition	2004	440
Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches Natilie Hosea, Wendy T. Collard, Susan Cole, The Journal of Clinical Pharmacology	2009	292
Elucidation of Distinct Ligand Binding Sites for Cytochrome P450 3A4 Natilie Hosea, Grover P. Miller, F. Peter Guengerich Biochemistry	2000	222
Evaluation of Selective γ-Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design Ping Wei, Marlena Walls, Ming Qiu, Molecular Cancer Therapeutics	2010	194
Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding Xingrong Liu, Bill J. Smith, Cuiping Chen, Journal of Pharmacology and Experimental Therapeutics	2005	182
Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration Xingrong Liu, Bill J. Smith, Cuiping Chen, Drug Metabolism and Disposition	2006	160
Mechanism of Oxime Reactivation of Acetylcholinesterase Analyzed by Chirality and Mutagenesis Lilly Wong, Zoran Radić, Roger J. M. Brüggemann, Biochemistry	2000	115
Simulation of Human Intravenous and Oral Pharmacokinetics of 21 Diverse Compounds Using Physiologically Based Pharmacokinetic Modelling Hannah M. Jones, Iain Gardner, Wendy T. Collard, Clinical Pharmacokinetics Physiologically Based PharmacokineticsPharmacokinetic ModellingPharmacodynamicsPharmacological StudyPhysiology	2011	111
Specificity and Orientation of Trigonal Carboxyl Esters and Tetrahedral Alkylphosphonyl Esters in Cholinesterases Natilie Hosea, Harvey Alan Berman, Palmer Taylor Biochemistry	1995	99
Reconstitution Premixes for Assays Using Purified Recombinant Human Cytochrome P450, NADPH-Cytochrome P450 Reductase, and Cytochromeb5 Peter Shaw, Natilie Hosea, David V. Thompson, Archives of Biochemistry and Biophysics Laboratory ProtocolBiochemistryMedicineNatural SciencesBioanalysis	1997	89

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