Concepedia

A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals

Thomas Peyret, Patrick Poulin, Kannan Krishnan

Toxicology and Applied Pharmacology · 2010 · 137 citations · 25 references

DOI

Concepts

References

25

Toxicity Testing in the 21st Century: A Vision and a Strategy

Daniel Krewski, Daniel Acosta, Melvin E. Andersen et al. · Journal of Toxicology and Environmental Health Part B · 2010 · 1.7K citations · Full text

, , +17

Principles and Methods of Toxicology

Food and Chemical Toxicology · 1984 · 1.4K citations

, , +10

Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Trudy Rodgers, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2006 · 940 citations

, , +11

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 774 citations

, , +13

Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2002 · 560 citations

, , +14