Concepedia

Model Building

Model Building is the systematic process of constructing a mathematical representation of pharmacokinetic behavior within a population by selecting structural, statistical, and variance components that best describe observed concentration-time data and inter-individual variability.

4.9K

Publications

300.2K

Citations

15.8K

Authors

3.8K

Institutions

Publications per year

2017–2026

1.4K

Variants

Pharmacokinetic Model Building

Parents

Children

Publications

4.9K

PLS-regression: a basic tool of chemometrics

Svante Wold, Michael Sjöstróm, Lennart Eriksson · Chemometrics and Intelligent Laboratory Systems · 2001 · 9.7K citations

, , +6

Auxiliary Variables in Mixture Modeling: Three-Step Approaches Using M<i>plus</i>

Tihomir Asparouhov, Bengt Muthén · Structural Equation Modeling A Multidisciplinary Journal · 2014 · 3.4K citations

, , +9

Group-Based Trajectory Modeling in Clinical Research

Daniel S. Nagin, Candice L. Odgers · Annual Review of Clinical Psychology · 2010 · 2.7K citations

, , +13

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

, , +12

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

, , +17

1–5 of 4.9K

Authors

15.8K

  1. LB
    Lewis B. Sheiner

    University of California, San Francisco, United States

    45 publications · 7.9K citations

    33

    h-index

  2. LA
    Leon Aarons

    University of Manchester, United Kingdom

    40 publications · 1.7K citations

    26

    h-index

  3. MO
    Mats O. Karlsson

    Uppsala University, Sweden

    41 publications · 3.9K citations

    25

    h-index

  4. FM
    France Mentré

    Inserm, France

    35 publications · 2.1K citations

    25

    h-index

  5. AR
    Amin Rostami‐Hodjegan

    University of Manchester, United Kingdom

    32 publications · 1.8K citations

    24

    h-index

1–5 of 15.8K

Institutions

3.8K

  1. University of California, San Francisco

    San Francisco, United States

    47 h-index

    134 publications

    20.9K citations

  2. University of Manchester

    Manchester, United Kingdom

    42 h-index

    238 publications

    15.3K citations

  3. Pfizer (United States)

    New York, United States

    39 h-index

    234 publications

    15.2K citations

  4. Center for Drug Evaluation and Research

    Silver Spring, United States

    38 h-index

    360 publications

    33K citations

  5. Roche (Switzerland)

    Basel, Switzerland

    38 h-index

    187 publications

    13.7K citations

  6. Uppsala University

    Uppsala, Sweden

    38 h-index

    263 publications

    17.4K citations

  7. Inserm

    Paris, France

    38 h-index

    265 publications

    13.5K citations

  8. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    35 h-index

    140 publications

    6.4K citations

1–8 of 3.8K

Venues

  1. CPT Pharmacometrics & Systems Pharmacology

    PSP · 168 publications · 11.1K citations

    51

    h-index

  2. Journal of Pharmaceutical Sciences

    112 publications · 8.5K citations

    48

    h-index

  3. Journal of Pharmacokinetics and Biopharmaceutics

    101 publications · 10.2K citations

    45

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 86 publications · 6.2K citations

    43

    h-index

  5. Journal of Pharmacokinetics and Pharmacodynamics

    134 publications · 7.6K citations

    41

    h-index

1–5