Concepedia

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland

Journal of Pharmaceutical Sciences · 2005 · 774 citations · 44 references

DOI

Concepts

References

44

Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2002 · 560 citations

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A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 423 citations

, , +8

Lipid composition of erythrocytes in various mammalian species

Gary J. Nelson · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1967 · 312 citations

, , +14

Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues

Paul van der Valk, C.K. van Kalken, Henk A. M. Ketelaars et al. · Annals of Oncology · 1990 · 242 citations · Full text

, , +14

Active Secretion of Drugs from the Small Intestinal Epithelium in Rats by P-Glycoprotein Functioning as an Absorption Barrier

Toshimitsu Terao, Etsuko Hisanaga, Yoshimichi Sai et al. · Journal of Pharmacy and Pharmacology · 1996 · 231 citations

, , +17