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A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Pharmacokinetic ModelingPharmacodynamicsPharmacological StudyPharmacometricsDrug DiscoveryPharmacologyMedicinePhysiologically-based Pharmacokinetic ModelingPharmacokineticsPlasma Partition CoefficientsPharmacodynamic ModelingPriori Prediction