A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Methotrexate Pharmacokinetics

Kenneth B. Bischoff, Robert L. Dedrick, Daniel S. Zaharko et al. · Journal of Pharmaceutical Sciences · 1971 · 479 citations · Full text

Principles and methods of toxicology

H.C. Krebs · Toxicon · 1995 · 327 citations

Pharmacy, Pharmacology, Toxicology +10

Tissue Concentrations of Clozapine and its Metabolites in the Rat

Ross J. Baldessarini, Franca Centorrino, James G. Flood et al. · Neuropsychopharmacology · 1993 · 232 citations

Medicine, Pharmacokinetics, Pharmacology +11

Interstitial fluid lipoproteins.

C H Sloop, Ladislav Dory, Paul S. Roheim · Journal of Lipid Research · 1987 · 228 citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +16

Computation of Brain−Blood Partitioning of Organic Solutes via Free Energy Calculations

Franco Lombardo, James F. Blake, William Curatolo · Journal of Medicinal Chemistry · 1996 · 198 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16