Concepedia

Tissue Partition Coefficients

Tissue Partition Coefficients is a physiologically based pharmacokinetic modeling parameter that quantifies the equilibrium distribution ratio of a drug between a specific tissue and blood, thereby characterizing the relative affinity of the drug for that tissue.

379

Publications

21K

Citations

1.4K

Authors

447

Institutions

Publications per year

2017–2026

32

Variants

Tissue-to-blood Partition Coefficients

Parents

Publications

379

Measurement of local cerebral blood flow with iodo [14C] antipyrine

O. Sakurada, Charles Kennedy, Jane Jehle et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1978 · 928 citations

, , +12

Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

Michael L. Gargas, Robert J. Burgess, Dale E. Voisard et al. · Toxicology and Applied Pharmacology · 1989 · 496 citations

, , +12

A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 423 citations

, , +8

Measurement of the Distribution Volume of Gadopentetate Dimeglumine at Echo-planar MR Imaging to Quantify Myocardial Infarction: Comparison with<sup>99m</sup>Tc-DTPA Autoradiography in Rats

Håkan Arheden, Maythem Saeed, C B Higgins et al. · Radiology · 1999 · 363 citations

, , +17

General approach for the calculation of tissue to plasma partition coefficients

Walter Schmitt · Toxicology in Vitro · 2007 · 354 citations

, , +8

1–5 of 379

Authors

1.4K

  1. PP
    Patrick Poulin

    Université de Montréal, Canada

    11 publications · 1.4K citations

    11

    h-index

  2. KK
    Kannan Krishnan

    Université de Montréal, Canada

    12 publications · 964 citations

    11

    h-index

  3. WE
    William E. Acree

    University of North Texas, United States

    9 publications · 355 citations

    9

    h-index

  4. MH
    Michael H. Abraham

    University College London, United Kingdom

    8 publications · 439 citations

    8

    h-index

  5. EI
    Edmond I. Eger

    University of California, San Francisco, United States

    6 publications · 672 citations

    6

    h-index

1–5 of 1.4K

Institutions

447

  1. Université de Montréal

    Montreal, Canada

    11 h-index

    25 publications

    2.2K citations

  2. University College London

    London, United Kingdom

    10 h-index

    18 publications

    783 citations

  3. University of North Texas

    Denton, United States

    10 h-index

    12 publications

    480 citations

  4. University of California, San Francisco

    San Francisco, United States

    9 h-index

    36 publications

    3.7K citations

  5. North Carolina State University

    Raleigh, United States

    8 h-index

    25 publications

    1.1K citations

  6. Research Triangle Park Foundation

    Durham, United States

    8 h-index

    18 publications

    541 citations

  7. University at Buffalo, State University of New York

    Buffalo, United States

    7 h-index

    26 publications

    842 citations

  8. National Institutes of Health

    Bethesda, United States

    7 h-index

    17 publications

    872 citations

1–8 of 447

Venues

  1. Journal of Pharmaceutical Sciences

    23 publications · 1.7K citations

    17

    h-index

  2. PubMed

    Repository · 16 publications · 505 citations

    13

    h-index

  3. Drug Metabolism and Disposition

    14 publications · 613 citations

    13

    h-index

  4. Journal of Toxicology and Environmental Health

    11 publications · 534 citations

    11

    h-index

  5. Anesthesia & Analgesia

    11 publications · 1.1K citations

    11

    h-index

1–5